时间:2024-12-23
Laparoscopic partial nephrectomy and robotic-assisted laparoscopic partial nephrectomy have been widely used with features of less invasiveness and quicker recovery.However,some complications such as pneumothorax or potential bleeding are uncommon but lethal.The approximate incidence rate of pneumothorax was 1%.Moreover,it could be detected in almost all laparoscopic or robotic operations and calls for prompt treatment[1].There are many reasons for pneumothorax,amongst which spontaneous diaphragm injury is one of the most difficult to discover.We present a lupus nephritis case with a long-term target treatment and hormone therapy who developed a pneumothorax during the operation.
8. I will play the lute, and you shall beat the kettledrum: A lute is a stringed instrument shaped like a pear with a long neck (Barnhart 727). A kettledrum is a drum made up of a thin hemispherical shell of brass28 or copper29 with a parchment top (Evans 603).Return to place in story.
A 39-year-old woman demanded the resection of her primary renal carcinoma after receiving 6-mo target therapy.
The patient was diagnosed with renal clear cell carcinoma with bone metastasis half a year ago.After receiving 6-mo target therapy,manifestations of bone lesions disappeared while the size of the renal mass increased.A partial nephrectomy was recommended for the treatment of her primary renal tumor.
The patient had been on hormone for lupus nephritis treatment for 17 years.
The patient reported no shortness of breath or chest pain at her first and second postoperative outpatient visits.
On arrival at the urosurgery ward,the patient’s blood pressure(BP)was 128/76 mmHg,and her pulse rate was 77 beats per minute(bpm).No percussion pain was detected alongside her urinary system.
As soon as she entered the ward,she received low-flow oxygen support with a nasal cannula,and her SpOwas maintained at 100%.A bedside chest X-ray(Figure 2)was ordered,whereas no evidence of pneumothorax or lib injury was found.Her spontaneous breathing SpOwas about 96%-98% on the first day after surgery.There were no other complications till the patient was discharged.
After careful evaluation,the patient was again set to the right lateral position,and the retroperitoneal COpressure was lowered to 10-12 mmHg.Laparoscopic exploration proved the integrity of the diaphragm:No injury or damage was found.The surgery was finished within the next hour,and the patient's SpOcould still be around 90%-94% after turning her back to a supine position.An extra 30-min pure Oinsufflation and lung dilation were performed until her SpOreached 100%.We transferred the patient to the post-anesthesia care unit and monitored her vital signs for more than 1 h.The patient claimed mild pain in her right chest during the monitoring.She was sent back to the urosurgery ward after her SpOwas sustained at 100% and all other vital signs were steady.
Hydrocortisone was prescribed as a premedication preoperatively.The patient's electrocardiogram,blood oxygen saturation(SpO),heart rate(HR),BP,body temperature,and end-tidal carbon dioxide(EtCO2)were monitored.Anesthesia was induced with 150 mg of propofol,10 mg of oxycodone,and 40 mg of rocuronium.The endotracheal intubation depth was 21 cm from the incisors.The anesthesia was maintained by inhaled sevoflurane and intravenous remifentanil.Ventilation parameters were set to volume-controlled mode(tidal volume at 6-8 mL/kg,respiratory rate at 10-12 times/min).As a result,the EtCOpartial pressure was about 31-44 mmHg,and airway pressure was maintained between 20-25 mmHg.
26.Godmother:The godmother did not become a common and well-known character in the Cinderella tale until Perrault incorporated her into his version of the story. Other versions of Cinderella in different cultures often have the heroine receive assistance from the deceased mother. The fairy godmother versions are the best known in Western culture thanks to Perrault and later versions from Disney and other sources.
The operation had to be ceased temporarily to set the patient's body position to supine.The anesthetist withdrew all intravenous medications and maximized the Osupply to 100%.Lung dilation was also conducted.However,after a 5-min resuscitation,her highest SpOcould only reach 92%.Arterial blood gas analysis showed that her partial COpressure was 47.5 mmHg,and blood lactic acid was 1.0 mmol/L.Due to the shielding of the metal part of the operating table,intraoperative X-ray was not feasible in this case.Intraoperative ultrasound of the right lung was conducted,and the result showed an advection requisition on M-mode(Figure 1).With this evidence,intraoperative pneumothorax was diagnosed.Residual retroperitoneal COwas released immediately.The patient's SpOcould be maintained at 94%-98%,and intraarterial pressure was controlled at 90-100/60-70 mmHg after 30 min of pure Oflow and lung dilation.Finally,her breath sound of the right lung could be heard again.
The patient was set to the right lateral position for laparoscopic partial nephrectomy.After establishing the retroperitoneal space,continuous COinsufflation was adopted to maintain the pneumoperitoneal pressure at 14 mmHg.The operation went on smoothly for half an hour,then suddenly,the patient's SpOdropped to 92%,while her HR increased to 106 bpm,and her BP increased from 80-90/60-65 mmHg to 106/80 mmHg.We paused the operation to recheck all equipment to make sure they were working well.Minutes later,her SpOdecreased to 85%-88%,and BP dropped to 80-85/50-60 mmHg like in a roller coaster.On the contrary,her HR increased to 116-125 bpm.The auscultation revealed that no breath sound of her right lung could be heard.Intraoperative pneumothorax was suspected,whereas pulmonary embolism could not be excluded,either.
A mass with mixing density was found on her left kidney on the enhanced computed tomography(CT).Its size was about 5.6 × 4.4 × 4.8 cm.
Nothing abnormal was shown in the laboratory examinations.
“There’s a Christmas wish contest on the radio station,” Amy’s mom announced. “Write a letter to Santa, and you might win a prize. I think someone at this table with blonde curly10 hair should enter.”
The final diagnosis of the presented case was left renal cell carcinoma with a history of bone metastasis.Intraoperative pneumothorax was diagnosed in this patient.
The simple-minded shepherd, who believed his story implicitly38, asked him, Do you think the king of the country would give his daughter to me? Yes, certainly, I know he would, answered Simon, if you were tied up in this sack instead of me
After pure Oflowing,lung dilation,and lowering the retroperitoneal COpressure,the patient's breath sound of the right lung could be heard again.Laparoscopic partial nephrectomy was performed successfully for this patient.
The patient had no markable personal and family history.
Any servant chore that princess performs is a kind of compensation to persuade the woman to become feminine again. The effect of animus pressure can lead a woman to deeper femininity, providing she accepts the fact that she is animus-possessed and does something to bring her animus reality (von Franz 174).Return to place in story.
Pneumothorax is one of the most dangerous complications during laparoscopic or robot-assisted laparoscopic operations.The literature review showed 11 cases of intraoperative pneumothorax that happened[2-3].The diagnosis of a pneumothorax always depends on ultrasound,X-ray,or chest CT scanning.Chest X-ray is usually the initial tool to detect potential cases.However,its application is limited in the operation room due to the inconvenience of fetching the equipment and low accuracy.
In contrast,transthoracic ultrasound has been reported to be a cheaper,more efficient,and more accurate source of evidence than chest X-ray with an 81%sensitivity and 100% specificity[4].The typical manifestation of pneumothorax under ultrasound is the multiple advection levels on M-mode,and the pleura moves without line B.X-ray or CT scan reveals the compression or atrophy of the lung.Intraoperative pneumothorax may result from:(1)Intraoperative diaphragm injury,including sharp instrument puncturing or thermal burning;(2)the congenital defection of the diaphragm,which was not discovered before the operation[5];and(3)high insufflation pressure and long surgery time[6].
Pneumothorax is sometimes misdiagnosed or confused with pulmonary embolism.In this case,we performed the arterial blood gas analysis to assess the patient's condition and exclude pulmonary embolism.An intraoperative ultrasound examination of the lung was also performed to seek more evidence of the pneumothorax.In this case,no injury or damage to the diaphragm was found before or during the operation.However,intraoperative exploration showed that her connective tissues and vessels were extremely fragile.Considering that cases had been sporadically reported,a 12-15 mmHg pneumoperitoneum pressure might cause intraoperative pneumothorax[3,7],while the insufflation pressure was set to 14 mmHg in this case.Given that this patient had a medical history of lupus nephritis and had been on hormone therapy for more than 10 years,we supposed that this might be the reason for the development of the pneumothorax,as COcould transfer from the retroperitoneal space to the chest under a higher insufflation pressure and a longer operation time.
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The treatment of the pneumothorax should be adjusted dynamically according to its cause and severity.Regardless,the COinsufflation should be discontinued,whereas endotracheal intubation,hyperventilation,and higher positive end-expiratory pressure should be maintained for lung dilation[8].In this patient,an insufflation pressure of 10-12 mmHg might be feasible as her renal tumor was located in the middle to lower kidney,where there was a relatively wider retroperitoneal space.However,in those where the tumors are particularly close to the diaphragm,lowering the retroperitoneal COpressure might interfere with the operation.
Pneumothorax is a rare but severe complication in laparoscopic or robot-assisted laparoscopic operations.It is sometimes neglected unless the injury or damage of the diaphragm is found.Intraoperative ultrasound is a convenient method for diagnosis.Low insufflation pressure and shorter operation time might be necessary for patients with a long-term hormone treatment history or chronic immune systematic disease.
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