Clear aligner treatment for a four-year-old patient with anterior crossbite and

INTRODUCTION

As a major problem of the primary dentition, anterior cross-bite affects approximately 25.29% of Chinese children, ranking third after deep overbite (33.66%) and spacing (28.34%)[1]. A study reported that 36% of subjects with anterior cross-bite exhibit functional shift[2]. Untreated anterior cross-bite could lead to an undesirable growth modification in which maxilla growth and dental development may be inhibited, which may eventually lead to severe skeletal deformity and cause aesthetic,functional, or sociopsychological problems[3]. In addition, children with untreated anterior cross-bites may have facial asymmetry due to tooth interference that may induce functional mandible displacement. If left untreated, this facial asymmetry tends to worsen, and causing an increased risk of craniomandibular disorders in adolescents and even temporomandibular symptoms[4].

Various methods have been used for primary dentition correction, such as removable transpalatal appliances with protruding finger springs, bonded resin-composite slopes and selective grinding[5,6].These correction strategies appeal to clinicians because of their simplicity. However, there are limitations to what can be achieved. Clear aligners have been widely used to treat malocclusions from crowding and extraction cases to orthodontic-orthognathic cases[7], and practitioners are exploring the border of it. Clear aligner treatment is patient-friendly, aesthetic-oriented, and offers significant benefits over conventional appliances in terms of comfort and aesthetics, which perfectly meets the need for orthodontic treatment in children. A longer clinic visit interval and fewer emergencies of clear aligner treatment are especially valuable in the time of the coronavirus disease 2019 (COVID-19) pandemic[8].This case report aims to explore the potential use of clear aligners in deciduous dentition, which would extend the application of clear aligners.

CASE PRESENTATION

Chief complaints

A 3-year-and-9-month-old female patient sought orthodontic treatment in her parents’ company, with a chief complaint of prominent lower anterior teeth and asymmetric face.

History of present illness

No history of present illness was reported.

History of past illness

No past illness was reported.

Personal and family history

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Physical examination

The patient was clinically assessed and fully investigated regarding oral hygiene, general health and medical history, which were unremarkable. No familial tendency of class III malocclusion was reported by the parents.

During clinical examination, a lateral shift of the mandible was observed. Her profile was minor concave, with protrusion of the upper and lower lips (Figure 1). The mandible could not be retracted to an edge-to-edge bite. The functional mandibular shift was detected, whereas nose-chin midpoints coincided when the mouth was wide open. No clicking sound or tenderness was detected in her temporo-mandibular joint area. Moreover, the clinical examination revealed mandibular displacement and habitual mandibular protraction with a deleterious tongue-thrust habit at rest and in speech.

Intraoral examination revealed a primary dentition phase. Anterior spacing was observed, and the model analysis showed 6.5 mm spacing in the maxillary arch and 5.3 mm spacing in the mandibular arch. The cross-bite involved the maxillary and mandibular incisors and the upper right canine with a maximum negative overjet of 4.5 mm and a negative overbite of 1.5 mm. The lateral view revealed a slightly palatal inclination of the upper incisors and a labial inclination of the mandibular incisors. The upper dental midline aligned with the facial midline, while the lower dental midline deviated 3.5 mm toward the right. Centric occlusion examination revealed a flush terminal molar relation with cross-bites on the right side and mesial step on the left side. In addition, an obvious sharp cusp was observed on tooth 53, implying insufficient tooth wear (Figure 1).

Imaging examinations

The lateral head radiograph was not performed owing to parent’s wishes and for ethical reasons[9].

FINAL DIAGNOSIS

National Nature Science Foundation of China, No. 31670992, and No. 31271052.

The patient was instructed to wear each aligner 22 h per day, even during school time. Nineteen aligners were scheduled, and a 5-day-change protocol was adopted because of the faster tooth movement during the deciduous dentition. A study reported that the activation force imparted by the aligner slowly decreases and plateaus within 5 d[10]. The duration of therapy was in line with conventional approaches.

TREATMENT

Treatment objectives

The following treatment goals were established: (1) Correct the etiological factors of habitual mandibular protraction and tongue thrusting; (2) Restore the normal inclination of the upper anterior teeth and close the spacing of the lower anterior teeth to establish a proper overbite and overjet; and (3)Improve facial aesthetics and symmetry

Treatment alternatives

Two treatment options were considered in this case. The first option was a removable appliance with protruding springs for the anterior maxillary teeth and selective grinding for the deciduous canine. The second option was using clear aligners.

Before being diagnosed in our clinic, the patient was initially treated with a removable transpalatal appliance that incorporated a bite plane and protruding springs. However, the treatment was interrupted because of discomfort. Moreover, the removable appliance is of no use for treating mandibular displacement. Additionally, the cusp of tooth 83 was tilted mesially to tooth 53, and tooth 53 slightly rotated in a mesial direction, which meant that grinding the cusps of tooth 53 was not an effective method. In this case, an Invisalign “Teen” package was chosen.

Treatment planning

Polyvinyl siloxane impressions were taken and sent to Invisalign

. Virtual planning of tooth movement in three dimensions was performed using ClinCheck

software (Align Technology, San Jose, CA, United States). The initial occlusion of this patient is shown in Figure 2A. Ellipsoid attachments were placed on the upper central incisors and the lower canines to improve retention, and rectangular attachments were placed on the occluding surfaces of the lower deciduous molars to obtain vertical clearance.

No familial tendency of class III malocclusion was reported by the parents.

Expansion and proclination of the upper anterior teeth were carried out first, with a small amount of intrusion and distal rotation of tooth 53 to relieve the occlusal interference. Simultaneously, the incisors were unlocked by bite attachments to seat bilateral condyles into a centric relation to solve the functional facial asymmetry. Subsequently, the upper anterior teeth were further proclined, and the lower anterior teeth were retracted to close the spacing, which could further coordinate the upper and the lower arches (Figure 2B). Meanwhile, slight extrusion of incisors was necessary to avoid the anterior open bites. Myofunctional therapies, including tongue elevation and correction of mandibular protraction habits, were performed in the process to ensure long-term stability.

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Interventions

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A monthly follow-up was planned to monitor the wearing. During the treatment, no detachment condition was reported. No self-perceived pain, discomfort or impairment of function was reported during treatment. When the patient wore the fourth aligner, her functional facial asymmetry was corrected as expected. The midlines of both arches were coincident, followed by the cross-bite of tooth 53 resolved and reserve overjet of teeth 52-62 reduced. At the same time, the posterior cross-bite was corrected (Figure 3A). The anterior cross-bite was almost corrected in the thirteenth aligner by modifying the maxillary incisors’ torque and closing the mandibular arch's spacing (Figure 3B).

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OUTCOME AND FOLLOW-UP

The total treatment time was 18 wk, and only 22 aligners were employed. The inclination of the incisors was improved to achieve an optimal overbite and overjet. Ideal canine and molar relationships and occlusion were established after correcting posterior cross-bite. The frontal smiling view revealed a coincident facial midline and the dental midline. The lateral view showed a straight profile with labially inclined upper incisors and improved facial aesthetics (Figure 4). In addition, the aberrant neuromuscular behavior of the mandible and the tongue was corrected after myofunctional therapy.

At the 6-month follow-up, although there was a minor relapse of spacing in the lower arch, an ideal occlusion was kept in both arches (Figure 5). Interestingly, tooth wear of cuspid 53 was observed,suggesting the establishment of canine-guided occlusion. The facial asymmetry was improved.

A 3-year follow-up at the age of 8 was recorded, and stability of the treatment was obtained in the mixed dentition. The permanent anterior teeth resulted in good positions, maintaining appropriate interincisal relations. An ideal symmetrical occlusion was achieved (Figure 6).

DISCUSSION

A functional mandibular shift commonly arises from tooth interferences or a narrow maxilla[17,18].In this case, occlusal interference caused by the insufficient wear of tooth 53 influenced the mandibular closing trajectory that forced the mandible to protrude and displace laterally, resulting in the posterior cross-bite and midline shift. Moreover, tongue habits have caused a transverse discrepancy in the arch relationship, specifically, a narrow maxilla with retroclined incisors and a mandibular arch with scattered space, facilitating anterior cross-bite. The mandibular shift from the centric relation (CR) to the intercuspal position is a key indicator diagnosing functional mandible displacement[19]. Mandibular displacement may be an expedient mechanism for postural adjustment consequent to occlusal disharmony and pain[20]. In our case, habitual asymmetric posture was observed as the midline deviation of the mandible left-deviated mandibular dental midline corrected itself as the mandible opened from a rest position. The mandibular dental midline patient widely opened her mouth from the resting position. The diagnosis of functional facial asymmetry would be more accurate after“deprogramming” the muscle memory.

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Suddenly, it dawned on me that I was dog-tired. I simply couldn t work as long as I could when I was younger. I ve got to rest for a minute, I told my husband, Roy, as I collapsed2 into my favorite rocking chair. Music was playing, my dog and cat were chasing each other and the telephone rang.

Class III malocclusion can appear early in deciduous dentition, and the deformity may vary from mild to severe throughout development. This malocclusion is often accompanied by varying degrees of mandibular deviation with few self-correction trends[11-13]. It is a mainstream perception that early intervention of class III malocclusion should begin early, at the primary dentition stage to curb the undesirable growth modifications during some of the most formative years, notwithstanding the controversy about the correct indication and stability[14,15].

Selective grinding of teeth is a simple treatment approach to correct the functional mandibular shift in the primary dentition[21]. However, it may not be favorable when the intercanine width differential is smaller than 3.3 mm or when a significant intermolar width discrepancy is detected[22]. Thus, in our case, grinding therapy may not have been satisfactory. Removable appliances are commonly used for anterior cross-bite correction. However, the discomfort was considered its main disadvantage, which would reduce treatment effectiveness and expand treatment duration, especially in young patients.Facemasks combined with auxiliaries, such as rapid palatal expanders, have also been reported for the correction of anterior cross-bites[5]. However, the lack of anchorage in deciduous dentition and the uncertainty about dental or skeletal effects limit the use of this device. In addition, side effects, including clockwise rotation of the mandible and extrusion of the molars, should not be neglected to prevent undesirable anterior open bite[23].

Compared with conventional removable or fixed appliances, clear aligners blend seamlessly with crown anatomy and thus possess the ability of three-dimensional, precise movement of the teeth.Furthermore, aligner thickness could provide adequate vertical clearance for cross-bite correction,avoiding the bulkiness of posterior capping, which could minimize traumatic occlusion or tooth wear during a cross-bite correction. Clear aligners can also prevent aesthetic drawbacks and speech impairment and can allow for optimal oral hygiene. This results in more positive patient feedback and significant improvements in children’s compliance[24].

The patient should be clinically assessed and fully investigated during treatment planning regarding dental, functional, profile and psycho-social correlations, oral hygiene, general health, and family history. Furthermore, there has been a lack of consideration regarding patient compliance and how it is a significant determinant of treatment outcome, especially in the treatment of young children[16].

In this case, tooth 53 was proclined with clear aligners to relieve the occlusal interference through the three-dimensional movement of intrusion and rotation. It is suggested that with more than 2/3 of vertical overbite to use bite ramps[25]. In our case, additional attachments were placed on the occlusal plane to provide vertical clearance for cross-bite correction. Subsequently, the anterior cross-bite was corrected through the expansion of the upper arch anterior teeth and the retraction of the lower anterior teeth. It is worth mentioning that because this patient had a shallow negative overbite, simple proclination of the upper anterior may cause anterior open bite and aberrant tongue-thrusting habits.Therefore, a slight extrusion of the incisors was designed to compensate. The bite block effects of aligner thickness also helped achieve better occlusal vertical control. During treatment, it was necessary to the check aligner fit at each follow-up to compensate for the poor retentive force due to the anatomically short crowns of the primary teeth. Additionally, clear aligner treatment is more efficient and effective for both patients and clinicians, with a long interval between follow-ups, fewer emergencies, or fewer negative side effects, especially in the unprecedented and unpredictable time of the pandemic[26].

CONCLUSION

This case reported the effectiveness of clear aligners in correcting anterior cross-bite and facial asymmetry in the primary dentition, obtaining a satisfactory and long-term stable outcome. Clear aligner therapy shows great potential in early intervention for deciduous teeth malocclusion due to its accurate three-dimensional tooth movement control, low cariogenic rate, and high coordination of children, which provides a new way to correct complicated cases of deciduous dentition. As encouraging results were achieved, the application of clear aligners might be limited under a thorough evaluation of benefits and burden. Further investigations are needed to standardize the treatment protocol.

FOOTNOTES

Zou YR and Gan ZQ contributed equally to this work; Zhao LX conceived and supervised the case; Zou YR and Gan ZQ performed the treatment and reviewed the literature and wrote the article.

The coaches were bewildered by his failure because he possessed3 all the characteristics of a superb athlete, but he couldn t seem to incorporate those advantages into a coordinated4 effort. He seemed to have become disconnected from his potential.

Based on these findings, the diagnosis was established as primary dentition with anterior cross-bite and functional facial asymmetry.

All study participants, or their legal guardian, provided informed written consent prior to study enrollment.

Margie always looked forward to the arrival of Christmas, and this year was no different as winter began to settle like a warm blanket around Colby Point. Everyone was in a flurry, for at the church Margie and her family attended, the congregation was preparing to share their Christmas wishes with each other. Since Cleo couldn’t make it to church, and Bill didn’t like to leave her alone for too long, he was in the habit of dropping Margie off at church early on Sunday mornings; the aunts would bring her home.

The authors declare that they have no conflict of interest.

The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BYNC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is noncommercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

They were immensely surprised at her appearance, but her charming face, and the deplorably ragged17 condition to which the thorns and briers had reduced her once elegant attire18, speedily won their compassion19; they recognised her as a companion in misfortune, and the Queen welcomed her heartily20, and begged her to share their simple repast

China

Yi-Ran Zou 0000-0001-9349-5978; Zi-Qi Gan 0000-0002-5573-8307; Li-Xing Zhao 0000-0002-9870-6436.

Liu JH

A

Liu JH

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