Effect of suspension training on neuromuscular function, postural control, and k

Dong-Dong Huang, Liang-Hua Chen, Zhe Yu, Quan-Jun Chen, Jie-Nuan Lai, Hai-Hong Li, Gang Liu

Dong-Dong Huang, Liang-Hua Chen, Zhe Yu, Quan-Jun Chen, Jie-Nuan Lai, Hai-Hong Li,Department of Rehabilitation Medicine, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, Guangdong Province, China

Gang Liu, Department of Rehabilitation Medicine, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong Province, China

Abstract BACKGROUND Suspension training (SET) is a method of neuromuscular training that enables the body to carry out active training under unstable support through a suspension therapy system. However, there have been few reports in the literature on the application of SET to anterior cruciate ligament reconstruction (ACLR) patients. It is not clear what aspects of the patient's function are improved after SET.AIM To investigate the effect of SET on the neuromuscular function, postural control,and knee kinematics of patients after ACLR surgery.METHODS Forty participants were randomized to an SET group or a control group. The SET group subjects participated in a SET protocol over 6 wk. The control group subjects participated in a traditional training protocol over 6 wk. Isokinetic muscle strength of the quadriceps and hamstrings, static and dynamic posture stability test, and relative translation of the injured knee were assessed before and after training.RESULTS The relative peak torque of the quadriceps and hamstrings in both groups increased significantly (P ＜ 0.001), and the SET group increased by a higher percentage than those in the control group (quadriceps: P = 0.004; hamstrings: P =0.011). After training, both groups showed significant improvements in static and dynamic posture stability (P ＜ 0.01), and the SET group had a greater change than the control group (P ＜ 0.05). No significant improvement on the relative translation of the injured knee was observed after training in either group (P ＞0.05).CONCLUSION Our findings show that SET promotes great responses in quadriceps and hamstring muscle strength and balance function in ACLR patients.

Key Words: Anterior cruciate ligament reconstruction; Suspension training; Neuromuscular function; Postural control; Knee kinematics; Rehabilitation

INTRODUCTION

Anterior cruciate ligament (ACL) rupture is common during sports and activities[1].ACL reconstruction (ACLR) is a frequent surgical procedure to restore functional joint stability after an ACL injury[1,2]. After ACLR surgery, the strength of the patient's injured limb is significantly reduced due to muscular atrophy and articular muscle inhibition[3,4], which increases the risk of re-injury of the knee joint and accelerates the degeneration of articular cartilage, leading to the development of osteoarthritis[5-8].Common physical therapy for ACLR patients includes instruction, bracing,cryotherapy, joint mobility training, muscle strength training, gait reeducation, and neuromuscular training[9,10]. Neuromuscular training is an important part of current ACLR rehabilitation[9]. Studies have shown that neuromuscular training can improve muscle strength, correct abnormal biomechanics, and enhance lower limb neuromuscular control, thus reducing the incidence of re-injury in ACLR patients[11-13].Myeret al[14]showed that a progressive, end-stage regressive neuromuscular training program could improve lower limb muscle strength and correct the abnormal distribution of plantar pressure in ACLR athletes. Kibeleet al[15]reported that neuromuscular training resulted in a significantly greater increase in knee stability by using a balance ball. However, Cooperet al[16]found that neuromuscular training with a balance board/Swiss ball did not significantly improve the muscle strength and balance function of ACLR patients. Therefore, different neuromuscular training techniques or different design schemes may lead to different rehabilitation effects.

Suspension training (SET) is a method of neuromuscular training that enables the body to carry out active training under unstable support through a suspension therapy system[17]. The training mode includes muscle relaxation training, joint motion training,traction, joint stability training, sensory and motor coordination training, and muscle potential energy training[18]. The personalized schemes of SET could be designed according to the different functional levels and functional requirements[19]. Moreover,this method has been widely used in the field of sports and rehabilitation because of its simpler operation and cheaper training equipment[19,20]. Studies have shown that adding SET to the rehabilitation program of healthy athletes can significantly improve quadriceps muscle strength[21]. In the field of rehabilitation, SET is mainly applied to bone and joint diseases, sports injuries, nerve injuries,etc.[20,22]. However, there have been few reports in the literature on the application of SET to the postoperative rehabilitation of ACLR patients.

Therefore, the primary purpose of the study was to determine the effect of SET on neuromuscular function, postural control, and knee kinematics in ACLR patients.

MATERIALS AND METHODS

Participants

A total of 40 patients were initially included in this study, and all underwent unilateral ACLR for the first time with a healthy opposite leg and volunteered to participate in a 6-wk intervention program after finishing 6-mo standard early rehabilitation. The inclusion criteria were: (1) Age 18 to 45 years; (2) ACL injuries diagnosed by arthroscopy or magnetic resonance examination; and (3) ACLR operation performed by the same experienced joint surgeon using a semitendinosus or gracilis tendon graft.The exclusion criteria were: (1) Previous injury or operation on the injured knee; (2)Joint injury that might influence the rehabilitation; (3) History of central or peripheral neurological impairment; and (4) Concomitant with any cardiac, pulmonary, or metabolic conditions. All admitted subjects provided informed consent in accordance with the Declaration of Helsinki[23]. All protocols were approved by the institutional review board.

Setting

All the patients were mainly recruited from the rehabilitation clinic and sports medicine clinic of the hospital. The rehabilitation treatment of the patients was completed in the rehabilitation center, and the evaluation was performed in the motor function assessment center.

Experimental design

This is a single-center, prospective, randomized, controlled clinical trial that followed the CONSORT guidelines. The sample size was based on the expected number of ACLR patients in the facility and previous pilot studies. Patients who met the criteria were randomized to an SET group or a control group according to a computergenerated form that was kept in a sealed, opaque envelope. A designated physician outside the team administered randomization. The primary investigators in charge of outpatient service were responsible for the recruitment, qualification, and allocation of patients. All data were analyzed by an experienced therapist who was blinded to the group information.

The SET group subjects participated in a SET training protocol over 6 wk, which included SET (twice weekly) and routine home rehabilitation (non-SET days). The control group subjects participated in a traditional training protocol over 6 wk, which included daily routine home rehabilitation (the supplement included detailed home rehabilitation program; Supplementary Table 1). Three patients later were excluded from the study for not complying with the course of rehabilitation. Consequently, 37 patients completed all protocol and testing sessions and were included in the data analysis (Figure 1).

SET

The SET group performed the SET program twice a week for 6 consecutive weeks.Four sets of 10-repetition maximum were performed for each exercise, with 1-2 min of rest between sets. A dedicated system of adjustable slings was used throughout the study with inelastic ropes (Figure 2). All treatments were performed by three designated therapists who strictly followed the designed program when implementing the patients' training program.

Affected side position:The patient was placed in the lateral position on the affected side with leaning on one elbow. With the anchor point of the suspension rope located on the superior border of the affected patella, the patient was supposed to place the affected leg on the adjusted suspension rope and press hard on the rope until the shoulder, hip, and leg were in line. The healthy leg was abducted to maximal joint angle and held for 2 s before returning to the starting position without being in contact with the sling ropes.

Figure 1 CONSORT flow diagram. SET: Suspension training.

Healthy side position:The patient was placed in the lateral position on the healthy side with leaning on one elbow. With the anchor point of the suspension rope located on the superior border of the affected patella, the patient was supposed to place the affected leg on the adjusted suspension rope and press hard on the rope until the shoulder, hip, and leg were in line. The healthy leg was abducted to maximal joint angle and held for 2 s before returning to the starting position.

Supine position:The patient was placed in the supine position. (1) He/she was supposed to keep his/her hands across the chest and place the affected leg on the rope with the anchor point of the suspension rope located on the popliteal fossa of the leg.And then, the affected leg was pressed hard down on the rope and the healthy leg was abducted to 45° joint angle and held for 2 s before returning to the starting position;and (2) The patient was supposed to hang both legs on the two ropes and place arms in contact with the floor. And then, he/she contracted the trunk and both knees and held the position for 2 s before returning to the starting position.

Prone position:The patient was placed in the prone position with leaning on their elbows. (1) He/she was supposed to place the affected leg on the rope with the anchor point of the suspension rope located on the superior border of the affected patella.And then, the affected leg was pressed hard down on the rope to lift the upper body,hips, and knees. The healthy leg was abducted to 45° joint angle and held the position for 2 s before returning to the starting position; and (2) The patient was supposed to place both legs on the two ropes. And then, they contracted their trunk and both knees and held the position for 2 s before returning to the starting position.

Figure 2 Suspension training program.

Isokinetic muscle strength test

The patients should perform regular warm-up exercises (10 min) on a bicycle dynamometer before the test. Muscle strength was evaluated using the concentric protocol module of IsoMed 2000 (D&R Ferstl). Before the formal test, the patients performed five repetitions of leg flexion and extension exercises to adjust to the test pattern. After a 2-min rest, the patients were asked to perform 10 repetitions with maximum effort at an angular velocity of 60°/s between 10° and 90° of knee flexion for both legs separately. The test of the uninjured leg was performed first and a rest for 5 min was given before another test mode. The symmetry index refers to the ratio index of the scaled peak moment on the injured side and the non-injured side.

Balance stability test

The balance was assessed by using a stabilometer platform (Tecnobody, PK 254, Italy).Two different test modes were performed, static posture stability test (level 12, stable platform) and dynamic posture stability test (level 4, unstable platform). The measurement of static postural stability involves the swing area of the center of gravity(Area). The higher score the Area index, the worse the static posture stability[24,25]. The measurement of dynamic stability includes the multi-axis mean trajectory difference(average trace error, ATE). The smaller the mean trajectory error, the better the proprioceptive sensitivity of the subjects[26,27]. Each participant was given three successful tests for each test mode.

Gait biomechanics test

Kinematic data of both knees were recorded and analyzed with a portable infrared optoelectronic motion capture system (Opti-Knee; Shanghai Innomotion Inc.). Before the test, each subject was required to walk on a test treadmill at a speed of 3 km/h to adjust to the test pattern. The gait cycle and the movement of the knee joint were tracked and recorded with a double-ended stereoscopic infrared camera and highspeed camera. Each participant was given three successful tests for each limb.

Data storage and analysis

All data were statistically analyzed using IBM SPSS Statistics Version 24.0 (IBM Corp,Chicago, IL, United States). The data are expressed as the mean ± SD with 95%confidence intervals. Independent-samplest-test and Fisher’s exact test were used to compare the baseline characteristics between the SET and control groups. The normal distribution of data was assessed using the Shapiro-Wilks test (P＞ 0.05), and homogeneity of variance (where appropriate) was tested by Levene’s test (P＞ 0.05).Differences between and within groups were performed. An independent-samplesttest was used to compare isokinetic muscle strength, balance function data, and gait biomechanics data between groups. A paired-samplest-test was used to compare isokinetic muscle strength, balance function data, and gait biomechanics data before and after rehabilitation.

RESULTS

For reasons unrelated to the study, three participants did not complete the study protocol, and only 37 patients completed the full rehabilitation program (SET group:n= 19, Control group:n= 18). There was no significant difference in any of the anthropometric variables between the two groups (Table 1). No adverse events occurred.

In terms of isometric muscle strength test, after 6 wk of training, the relative peak torque of the quadriceps and hamstrings in the injured leg of both groups increased significantly (P＜ 0.001) (Figure 3), and the relative peak torque of the quadriceps and hamstrings in the injured leg of the SET group increased by a higher percentage than those in the control group (P= 0.004 andP= 0.011). There was no significant difference between the SET group and the control group in the increased percentage of the relative peak torque of the uninjured leg (Figure 4A). The symmetry index of the quadriceps femoris in both groups was significantly higher than that before training(SET:P= 0.001, Control:P= 0.034). In the SET group, the hamstring symmetry index of the operative leg increased significantly (P＜ 0.001), while the hamstring symmetry index of the control group did not change significantly (P= 0.063) (Figure 4B).

In the balance stability test, significant decline of Area and ATE were observed in both groups (P＜ 0.001), and the SET group had a significantly greater decrease than the control group (P＜ 0.05) (Table 2). In the gait biomechanics test, there was no significant difference in relative translation of the injured knee in either group after training (P＞ 0.05) (Table 3).

DISCUSSION

This study is the first to examine the effect of SET in the ACLR rehabilitation program.The main findings of this clinical study are as follows: (1) SET resulted in a significant increase in quadriceps and hamstring muscle strength and strength symmetry; (2) SET resulted in greater improvements in the balance stability of the lower limbs; and (3)SET had a limited effect on the injured knee kinematics.

Muscle strength

The functioning of quadriceps and hamstring muscles is a critical factor in the patients'ability to prevent reinjury after ACLR surgery[1,28]. Consequently, it is of great importance to regain quadriceps and hamstring strength after surgery. Similar to previous studies, we found that our patients did not fully regain the muscle strength of their reconstructed leg despite a 6-mo intensive rehabilitation program[29]. The main causes of muscle weakness include poor neuromuscular control and substantial muscle atrophy, which are also major risk factors for the postoperative reinjury of the knee joint[28].

SET is a special kind of neuromuscular training, and previous studies have shown that neuromuscular training can improve strength[21]. Therefore, adding SET to an athletes' rehabilitation program can significantly enhance the power of the quadriceps[30]. Furthermore, the application of SET to patients after knee arthroplasty can achieve a better rehabilitation effect[22]. In this study, SET was applied to the postoperative rehabilitation of ACLR patients. After SET, the relative peak torque of the quadriceps and hamstrings in the injured leg of the SET group showed greater improvements than before. The SET group demonstrated a more significant percentage of change in isokinetic torques of the injured leg than the control group. It can be speculated that the use of SET training resulted in a significant improvement in quadriceps and hamstring strength. Meanwhile, compared with conventional training,SET can more quickly improve muscle strength and shorten the development periodof rehabilitation.

Table 1 Subject demographics

Table 2 Results of balance stability test before and after training

Table 3 Results of gait biomechanics test before and after training

In this study, SET obtained reliable results in improving the symmetry of the lower limb strength in ACLR patients. Since the training program focuses on the rehabilitation of the injured leg, there was no difference in the increased percentage of the uninjured knee strength between the two groups. In the design of the SET program, open kinetic chain exercises and closed kinetic chain exercises were combined. The movements (A, B, C, and E) follow the same pattern as the open chain movement of the healthy leg and the closed chain movement of the injured limb.Previous studies have confirmed that the rehabilitation program for ACLR patients can obtain a greater improvement of the rehabilitation effect after the combination of the open kinetic chain and closed kinetic chain[31]. The strength of the quadriceps muscle is a critical factor for the stability of knee joints in patients after ACLR surgery[4,28]. SET could be targeted to activate the weak chain of the muscle of the lower limb[32,33]. A report has confirmed that both close-chain and open chain movements under SET can greatly activate the quadriceps femoris[21]. Due to severe muscle atrophy after ACLR surgery, muscle asymmetry is considered a risk factor for secondary knee injury[3]. The quadriceps index and hamstring index can well reflect the symmetry of the strength between the injured side and the contralateral side. A larger index is associated with a better symmetry of bilateral strength[28]. In our study,we found that the quadriceps and hamstrings peak torque of the injured side recovered to “75%” and “57%” of the contralateral side before training in the SET group. After training, the injured side's quadriceps and hamstring indexes were “93%”and “72%”, respectively, which were significantly improved compared with the control group. It can be speculated that SET has a more significant effect on the improvement of the double lower limb strength symmetry. This finding suggests that adding SET to the rehabilitation process could effectively improve the muscle strength and symmetry of the lower limbs, which helps to reduce the risk of re-injury of the reconstructed ACL in ACLR patients.

Figure 3 Scaled peak torque of the quadriceps and hamstrings of the injured leg. aP ＜ 0.05 indicates a significant difference between pre-training and post-training. SET: Suspension training.

Figure 4 Percent change and symmetry index of the scaled peak torque. A: Percent change of the scaled peak torque pre- to post-training; B:Comparison the scaled peak torque between the injured side and the non-injured side. SET: Suspension training.

Balance stability

After 6 wk of training, static balance and dynamic balance were improved in both groups, and the SET group had a greater improvement than the control group. This result was expected given that the balance stability of the lower limbs is significantly related to the ability of neuromuscular control. What's more, dynamic balance stability is not only related to the local stabilizing muscles around the joint but is also affected by the stability and coordination of the other muscles of the body[34].

Studies have proven that training with an unstable plane results in the high internal contraction of muscles and overloading if the instability difficulty of this plane is moderate, providing an effective training environment for muscles[14,15,35]. However,most of the recommended core training modes only work in one or two motion planes[12]. The key of SET is motion control. By providing a three-dimensional unstable training environment, the subjects were required to perceive the position of the body in three-dimensional space to maintain the stability of the position. The instability of the training plane is higher, and the core muscles of the patient can bear more exercise load during the training[32]. SET can promote the coordinated contraction of the trunk,hip, and knee, recruit more muscle groups, and activate local stable muscle groups during the coordinated contraction of the overall muscles, which is helpful to improve the dynamic balance function of the lower limbs[33]. It can be inferred that the application of SET to ACLR patients can not only effectively activate the strong contraction of the trunk and lower limb muscles and improve the neuromuscular control ability but also promote the strength growth of local muscles around the knee joint[36], thus enhancing the postural control of ACLR patients.

Knee kinematics

In the present study, we discuss the injured knee kinematics by performing a calculation of the relative motion of the tibial femur joint. However, there was no significant improvement in both groups after training. The relative displacement of the knee joint on the coronal plane mainly reflects the varus and valgus of the joint.Moderate rotation of the tibia occurs during a normal gait cycle, while anteriorposterior and proximal-distal relative translation reflects the track of the tibial femur joint in the sagittal plane[37]. The relative motion of the tibial femur joint was affected by soft tissue and muscle around the knee. In this study, muscle strength around the knee joint was increased equably after training, which avoided the significant kinematic changes of the knee joint due to the imbalance of the strength. It is known that factors affecting the motor function of the lower limbs include the coordinated movement of multiple joints and muscles, and changes in the hip and ankle joints will also affect the walking pattern[38]. In addition, ACLR patients experienced a long period of knee braking in the early postoperative period, resulting in error motor adaptation[39]. It can be speculated that short-term training has a very limited impact on unilateral joint movement. Future studies will be needed to design a long-term,systematic SET program and explore its impact on the biomechanical changes of the hip and ankle joints of ACLR patients.

CONCLUSION

In conclusion, SET promotes great responses in quadriceps and hamstring muscle strength and balance control in ACLR patients. More importantly, the SET program designed for ACLR patients is worthy of clinical promotion, and it also has reference value for the design of SET programs for other orthopedic postoperative patients.

ARTICLE HIGHLIGHTS

Research background

Suspension training (SET), a method of neuromuscular training that enables the body to carry out active training under unstable support through a suspension therapy system, has been widely used in the field of sports and rehabilitation. However, there have been few reports in the literature on the application of SET to the postoperative rehabilitation of anterior cruciate ligament reconstruction (ACLR) patients.

Research motivation

We hope to explore the effect of SET on neuromuscular function, postural control, and knee kinematics in ACLR patients.

Research objectives

To compare the clinical efficacy between SET protocol and traditional training protocol in ACLR patients.

Research methods

Forty participants were randomized to an SET group or a control group. The SET group subjects participated in a SET protocol over 6 wk. The control group subjects participated in a traditional training protocol over 6 wk. Isokinetic muscle strength of the quadriceps and hamstrings, static and dynamic posture stability test, and relative translation of injured knee were assessed before and after training.

Research results

A total of 37 patients were included in the final analysis (SET group, n = 19; control group, n = 18). The relative peak torque of the quadriceps and hamstrings in both groups increased significantly (P ＜ 0.001), and the SET group increased by a higher percentage than those in the control group (quadriceps:P= 0.004, hamstrings:P=0.011). After training, both groups showed significant improvements in static and dynamic posture stability (P＜ 0.01), and the SET group had a greater change than the control group (P＜ 0.05). No significant improvement on the relative translation of injured knee was observed after training in both groups (P＞ 0.05).

Research conclusions

SET can improve the postoperative rehabilitation effect of ACLR patients and is worthy of clinical promotion.

Research perspectives

We only focused on the effect of SET on the injured knee. Thus, further studies should be performed to explore its biomechanical impact on the hip and ankle joints of ACLR patients and provide more evidence for the clinical application of SET.